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Both mutations are in exon 7 of the G6PD gene

1, 2020, U.S

Simultaneously, it induces LSEC dysfunction and capillarization, while promoting macrophage M1 polarization (Nian et al., 2024)

To date, there have been many studies that have covered the negative impact of the ApoE4 + variant, and they are generally linked with dysplidiemia, glial dysfunction with lipid accumulating in microglia and astrocytes (Haney et al., 2024