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J Biol Chem (2014) 289:191729

Myers et al

Even though Apo Lf decreased neuronal iron accumulation with a visible iron chelation effect, the main effect presumably was either restoration of mitochondrial function or protection of neurons from toxicity-induced apoptosis (Wang et al., In another similar research, pretreatment of human Lf (hLF) in an MPTP-mediated mouse model of the nigrostriatal system was performed