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Melanoma-associated antigen A6 (MAGEA6) with oncogenic activity is highly expressed in triple-negative breast cancer (TNBC) cell lines and tumor tissues and is involved in the acquisition of drug resistance

However, deletion of MLKL or inhibition of RIPK1 in macrophages does not completely rescue Mtb-infected cells from death, 84,101 suggesting that, although the deficiency of MLKL or RIPK1 can abrogate the canonical necroptosis pathway, upstream TNF/TNFR1-mediated signaling may stimulate the induction of other cell death pathways during Mtb infection

While IN DFO has been extensively studied in preclinical models of Alzheimers disease and stroke, recent developments have expanded the scope to other chelators such as DFP

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