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Description

ALG12-CDG is due to deficiency of ALG12 1,6-mannosyltransferase that adds the eighth mannose residue on the dolichol-PP-oligosaccharide precursor in the endoplasmic reticulum

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This detoxification process ensures nerve cells have the optimal conditions for repair and regeneration

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Aberrant protein synthesis and cancer development: the role of canonical eukaryotic initiation, elongation and termination factors in tumorigenesis

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