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Brain Research Bulletin , 161, 2938

Am J Transl Res (2017) 9(7):3399410

Celastrol inhibits rheumatoid arthritis through the ROS-NF-B-NLRP3 inflammasome axis

Patients and clinicians often misinterpret the neurologic signs and symptoms of vitamin B12 deficiency as those of diabetic neuropathy.2 Also, vitamin B12 deficiency can increase the severity of peripheral neuropathy in patients with T2DM.6 In addition to memory impairment, neurocognitive symptoms attributable to B12 deficiency include confusion, personality changes, delirium, and depression