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Metformin treatment confers protection of the optic nerve following photoreceptor degeneration

By inhibiting NNMT, it essentially takes the foot off that metabolic brake

J Thromb Haemost 14(7):14421452

A total of 40 participants were selected and randomized into two sequences in a double-blind, placebo-controlled crossover design, with a one-week washout period between treatments to eliminate carryover effects