clozapine glutathione adduct The metabolism of clozapine. In the liver, is metabolised to Neutrophil Cytotoxicity of the Chemically
Neutrophil Cytotoxicity of the Chemically Reactive Metabolite(s) of Clozapine: Possible Role in Agranulocytosis ScienceDirect Identification and quantification of glutathione adducts of clozapine using ultrahighperformance liquid chromatography with orthogonal acceleration timeofflight mass spectrometry and inductively coupled plasma mass spectrometry MacDonald 2011 US6197764B1 Clozapine compositions and uses thereof Google Patents A novel quantitative assessment of formed reactive metabolites by double trapping with [3H]glutathione and [14C]cyanide ScienceDirect
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