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This might be because the high level of NO radical in M1 cells easily reacts with active intermediates produced by lipid free radicals and lipid peroxidation, and then replaces GPX4 to prevent ferroptosis [128, 129]

Some may notice minor side effects at first, such as feeling a bit flushed, a touch dizzy, or maybe getting a headache

Topical GSH can be used alongside mild pigment inhibitors, such as arbutin or tranexamic acid

All animal experiments in this study were performed in strict accordance with the institutionally approved protocol according to the USPHS Guide for the Care and Use of Laboratory Animals and with the approval of the Institutional Animal Care and Use Committee of the South China University of Technology