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In MS lesions, BDNF is primarily present in immune cells and reactive astrocytes (98), while the BDNF receptor TrkB was strongly upregulated in reactive astrocytes and in neurons in the immediate lesion vicinity (98)

10.1016/j.carbpol.2012.03.029 209 WangS

Dual pH- and thermo-sensitive poly(N-isopropylacrylamide-co-allylamine) nanogels for curcumin delivery: swelling-deswelling behavior and phase transition mechanism