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Clinical trials in humans evaluating lipotropic injections remain scarce

It is essential for attending physicians to develop a treatment approach for geriatric patients and conduct regular clinical evaluations to ensure optimal outcomes

Accordingly, it was shown that deacetylation of FOXO3 by Sirt1 and Sirt3 enhanced the FOXO3-mediated transactivation of genes responsible for cell cycle arrest, DNA repair, and ROS neutralization, along with the attenuation of pro-apoptotic genes [81, 89, 90]