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GLP-1 receptor agonists are peptide-based medications

2396-C WESTERN DIET DAMPENS T REGULATORY CELL FUNCTION TO FUEL HEPATIC INFLAMMATION IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE Sudrishti Chaudhary 1 , Ravi Rai 1 , Pabitra Pal 1 , Dana Tedesco 2 , Aatur Singhi 3 , Satdarshan (Paul) Monga 1 , Arash Grakoui 2 , Smita Iyer 1 and Reben Raeman 1 , (1)University of Pittsburgh, (2)Emory University School of Medicine, (3)University of Pittsburgh Medical Center Background: The immunosuppressive T regulatory cells (Tregs) regulate immune responses and maintain immune homeostasis, yet their functions in metabolic dysfunction-associated steatotic liver disease (MASLD) pathogenesis remains controversial

Participants drank one cup and two cups of decaffeinated Italian espresso in random order, with 57 days between test sessions

This review aims to catalyze further research in this underexplored area, emphasizing the potential of lipid peroxidation products to hinder the clinical translation of ferroptosis-based therapies