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Description

Over the past decades, a variety of downstream effector pathways and their connectivity have been elucidated [8], and it has been suggested that the conformational plasticity of GPCRs [9] and GPCR-transducer complexes also contribute to biased signaling and complexities of GPCR signaling [10, 11]

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On the other hand, recent study with novel bis-AIAs revealed their higher potency and analysis showed DNA as the main target, but no DNA ultrastructural alterations were found [149]

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MNs provide a minimally invasive method of connecting with the brain, providing direct and stable neural signal detection and modulation connections

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Int J Mol Sci 2020, 21:8113

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