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In addition, protective and prophylactic measures, such as administration of nephroprotective agents including safe antioxidants and anti-inflammatory agents as supplementation, to decrease the incidence of ESRD among RA patients should also be established

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AhpC-disulfide is subsequently reduced by AhpF, a close homologue of bacterial TrxR that can use either NADPH or NADH as a source of reducing power