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10.1016/s0090-9556(25)06654-1 148 KurajohM.FukumotoS.YoshidaS.AkariS.MuraseT.NakamuraT.et al (2021)

the pathway briefly reconstituted by the addition of methylcobalamin alone will sputter, like an unused engine, creating inefficient function, and an imbalance of related methylation reactions producing an abundance of pathway inhibiting substances like SAH

The clinical term for this is hyperprolactinemia , which is simply a medical way of saying you have too much of the prolactin hormone circulating in your blood

According to one study, Ipamorelin may have induced an apparent increase, by approximately 15%, in body weight of the research models