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Between the two baseline samples, Lachnospiraceae was significant higher in the placebo baseline ( p -value Lachnospiraceae = 0.046)

These additional excretion pathways collectively contribute to maintain TMAO balance in the body ( In summary, TMAO metabolism involves converting dietary choline to TMA by gut microbes, oxidizing TMA to TMAO in the liver, and primarily excreting TMAO via the kidney, with minor elimination through sweat, feces, and breath