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Emodin Targets ErbB signaling and alters dopamine and serotonin metabolism to exhibit ameliorating effects against schizophrenia symptoms (Mizuno et al., 2008

revealed that endogenous metabolites of vitamin E, particularly -13-COOH, exert anti-inflammatory effects by directly inhibiting 5-lipoxygenase (5-LO), a key enzyme in leukotriene biosynthesis