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Several studies report increased circulating platelet microparticles and elevated platelet activation markers (for example, SCUBE1 and platelet arginase activity) in women with PCOS, findings that implicate heightened platelet responsiveness and a greater reservoir of vesicular mediators capable of modulating neutrophil behavior [75]

Notably, the deletion of Slc7a11 (which encodes xCT) in animals results in viable offspring 15 , which suggests that tissues (and potentially tumours) can obtain cysteine from another origin

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