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Inhibition of ME2 inhibitor-binding site mutants with MDSA or EA Based on the structures of ME2-EA and ME2-MDSA, we designed 16 ME2 mutants and assessed their susceptibility to MDSA or EA inhibition to determine which amino acid residues are required for MDSA or EA binding and inhibition (Fig

The protective effect of (-)-epigallocatechin-3-gallate on arsenic-induced cardiotoxicity was evaluated in vivo and in vitro , and the mechanism may be attributable to its potent antioxidant capacity