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Gholami et al also found a decrease in the content of endothelial cells in the CC of the high-cholesterol rat model [126]

That's the process

Understanding the functional implications of these gene polymorphisms contributes to the application of precision medicine, as they can serve as potential markers for drug selection and dosage adjustment during initiation treatment of immunosuppressant to enhance treatment efficacy, minimize toxicity, and improve outcomes for SLE patients

The clinical trial reported percentage weight loss rather than absolute weight, so researchers should calculate expected absolute weight changes based on the starting weight of their research subjects when designing study endpoints