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The high-affinity binding of nicotine to 5 subunit-containing receptors on MHb neurons triggers Ca 2+ -dependent burst firing, which induces the axonal terminal release of glucagon-like peptide-1 (GLP-1)

The changes of the protein expression levels of NDUFS1, NDUFV2, SQSTM1, SDHA, and ERO1A are further validated by immunoblotting analysis

Here, we present the validated tool for the detection of anti-GX-G3 antibodies and report a potential immunogenicity which affects to GX-G3 toxicokinetic data in nonclinical rat and monkey studies subcutaneously administrated with GX-G3 for 4 weeks followed by a 4-week recovery period

Plant Signal Behav 12(8):e1356531