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Description

Vertebral endplate trauma induces disc cell apoptosis and promotes organ degeneration in vitro

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Loss of inhibitory motor innervation of the sphincter of Oddi elevates pressures in biliary tract ducts, distends the ducts, and causes acalculous biliary pain

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Reference: Kelley KW, Weigent DA, Kooijman R

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Typical daily range: 300500 mcg once daily, often fasted or pre-workout, raised gradually over an 816 week course

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