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In protein modification, glyoxal and MG act as potent glycating agents, generating lysine-derived adducts (CML and CEL residues), bis(lysyl) crosslinks (GOLD and MOLD), and AGEs (G-H1 and MG-H1)

We next used the transgenic strains to examine the tissue-specific expression of RIPS-1 and found specific transgene expression in the cytoplasm of the gut and hypodermal cells following treatment with 5 mM DTT (Fig