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Patients with this type of anemia also often present with Hypersegmented Neutrophils on a blood smear, which is a neutrophil with 5 or more segments in the nucleus

These include, but are not limited to, the thiamine transporter, alpha(2,3)- sialoglycoprotein receptor, transferrin receptor, scavenger receptors, LDL receptors, LRPlB, LRP2, DTR, insulin receptor, IGF receptor, leptin receptor, mannose 6- phosphate receptor

This is usually utilised for mammalian immunological defence, but also plays a role in cell signalling

Participates in the biosynthesis of many neurotransmitters, such as dopamine, norepinephrine, adrenaline, histamine and GABA, participating in the exchange of glutamic acid