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Alogliptin (10 mg/kg/d for 4 weeks) prevented thoracic aortic constriction (TAC)-induced cardiac alterations in C57BL6mice

Unlike other amino acids, aspartate is not involved in catabolism but rather serves as an amino acid exchange factor for retrograde transport to absorb essential amino acids and balance intracellular or extracellular levels of other amino acids including glycine, histidine, serine, and threonine (67)