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and accordingly nerve damage appeared in various brain areas, with most prominent damage in corpus callosum, laterodorsal thalamus, nucleus reunions, anterior horn motor neurons, regional heterogeneities which suggest differences in the underlying pathophysiology as it had been previously claimed (72)

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Oxidative stress has long been associated with diabetic complications, but has only recently received attention as a possible reason for the development of diabetes (Houstis et al., 12 deficiency may be a major factor responsible for impaired GSH levels