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Omarigliptin decreases inflammation and insulin resistance in a pleiotropic manner in patients with type 2 diabetes

Carnitine supplementation may have beneficial effects on glucose homeostasis also by modulating the expression of genes involved in insulin signaling pathway, changing the expression of gluconeogenic and glycolytic enzymes, regulating the intra-mitochondrial acyl-CoA/CoA ratio, and modulating the activity of pyruvate dehydrogenase complex (Steiber et al., 2004[46])

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