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Before increasing dose, evaluate the non-pharmacological variables

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This syndrome has been reported to be more likely if the patient has abnormal kidney function.9 Although there is some significant debate on this point10, it is generally agreed that patients with abnormal kidney function should start allopurinol at low doses and build up, to ensure that the allopurinol is effectively excreted

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Glutathione is composed of: Glutamate Cysteine Glycine Its unique gamma-peptide bond between glutamate and cysteine contributes to its stability and biological activity in redox reactions

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