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Breen et al

3, the PI3K/Akt/mTOR pathway is known to influence iron metabolism and ferritinophagy

56 CicchettiF.LapointeN.Roberge-TremblayA.Saint-PierreM.JimenezL.FickeB

Results from these multi-scale approaches reveal that cysteines 8 and 83 are the main targets of glutathionylation and oxidation that lead to loss of activity, while cysteine 79 is less vulnerable to oxidation