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Proteolysis was initially reduced in sensitive seedlings in response to water deficiency

Cohen PL, Cheek RL, Hadler JA, Yount WJ, Eisenberg RA

This is followed by loss of nigrostriatal dopaminergic neurons, with patients exhibiting manifestations such as depression, sleep disturbances, and cognitive dysfunction [22]

B12 then is unable to bind to IF, which is needed in order to be absorbed in the small intestine for use throughout the body.Pernicious anemia is the most common cause of B12 deficiency in the UK, according to the National Health Services