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Kim et al., 2011), ULK1-associated ATG13 (Jung et al., 2009), and ATG14 (Yuan et al., 2013), which disrupts autophagy induction and autophagosome nucleation and maturation

Quinones Sennoside A (SA) is a major anthraquinone active ingredient in rhubarb, with anti-inflammatory, anticancer, antiviral, and anti-neurodegenerative properties

Chemotherapy resistance mechanisms were linked to evasion of apoptosis and ferroptosis, increased drug inactivation, decreased drug activation, changes in drug transport, modulations in drug targets, and interactions with components of the TME, such as cancer-associated fibroblasts and tumor-associated macrophages

In a mouse model, supplementation with VD induces an anti-inflammatory phenotype in macrophages and exhibits anti-proliferative properties (123)