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BioMed Research International (2015)

These limitations have driven decades of research into smaller molecules that can activate TrkB signaling with better pharmacokinetic properties

The ability of the cognitively active fragments described here to support hippocampal spinogenesis was tested and the results are presented in Figure 31A-D.As can be seen from the dose-response curves, each of the metabolically stabilized molecules supported hippocampal spinogenesis

Presented as a freeze-dried powder, this format is selected to maximise stability during storage and handling while allowing researchers to prepare solutions according to the specific requirements of their experimental protocols