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Among the 77 infants tested at 6 weeks of age, the median blood vitamin B 12 level was 199 pmol/L (270 ng/L) in the supplemented group and 139 pmol/L (188 ng/L) in the placebo group.[23] Sixty-eight pregnant women in Bangladesh received 250 mcg oral vitamin B 12 capsules or placebo once daily beginning during their first trimester of pregnancy and continuing until 3 months postpartum

Moreover, peer-reviewed research describes poor oral bioavailability, which helped motivate development of the orally active analog SLU-PP-915