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Further more, oxidized DNA is more resistant to degradation by cytosolic nucleases (Gehrke et al., 2013), therefore oxidants can promote the accumulation of DNA in the cytosol, and potentiate the activation of the cGAS-STING pathway (Gehrke et al., 2013)

All mice were fed standard rodent chow (PicoLab 5053, LabDiet) and housed in a specific pathogen-free facility at a controlled temperature of 2223 C on a 12-h lightdark cycle

IJET 7:788793 Baca-Lopez K, Fresno C, Espinal-Enriquez J, Martinez-Garcia M, Camacho-Lopez MA et al (2021) Spatio-temporal representativeness of air quality monitoring stations in Mexico City: implications for public health

Continuing research is required to find alternative biomarkers that can be employed for the early detection and improved management of CRC