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This proliferative halt may indirectly reduce basal levels of cellular anabolism and reactive oxygen species (ROS) generation, thereby enhancing resistance to ferroptosis (108)

The Impact of Next-Generation Sequencing on Interobserver Agreement and Diagnostic Accuracy of Deep Penetrating Melanocytic Neoplasms

The reaction formula can be summarized as follows: 2 GSH GSSG + 2H + 2e (under the action of GPX or ROS) However, to prevent GSSG accumulation from disrupting the intracellular sulfhydryl balance, cells need to rapidly convert it back to GSH through an efficient reduction system