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Administering antioxidants prior to or alongside gonadotoxic treatments may mitigate ROS induced damage to spermatogenic cells, thereby preserving endogenous sperm production

doi: 10.1016/j.coph.2007.04.006

Reduced glutathione (GSH) is a major intracellular antioxidant neutralizing free radicals and detoxifying electrophiles

However,translating success from a sterile laboratory mouse to a human living with complex, multi-factorial Crohn's disease or ulcerative colitis is incredibly difficult