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This research was conducted within the context of the CNRSImperial International Research Project METABO-LIC

To position CBS upstream of cysteine and GSH

An important role of GSSG in the NFkappaB activating signal cascade is suggested by the facts that the potent NFkB inducer, tetradecanoyl phorbol acetate, increases intracellular GSSG levels and GSSG/GSH ratios