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Exposure-specific terminology featured Smokeless Tobacco[MeSH], Tobacco, Smokeless[MeSH], Tobacco Use[MeSH], together with keywords snus, chewing tobacco, naswar, toombak, gutka, betel quid, and nicotine pouch. Outcome-related terms included Oral Mucosa[MeSH], Mouth Diseases[MeSH], Leukoplakia, Oral[MeSH], Periodontitis[MeSH], Carcinoma, Squamous Cell[MeSH], and free-text keywords such as oral lesion, keratosis, gingival recession, dental caries, oral squamous cell carcinoma, oral cancer, cytokines, IL-6, IL-8, and TNF-alpha. Boolean operators (AND/OR) were used to combine search terms appropriately

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The sperm epigenome, far from being a passive carrier of genetic material, emerges as a dynamic and environmentally sensitive system capable of transmitting acquired risk across generations

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