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Being a tall, thin male Scuba diving, flying, or climbing to high altitudes Smoking Lung conditions such as cystic fibrosis, COPD, emphysema, pulmonary fibrosis, or severe asthma A lung infection, such as pneumonia or TB A tumor, such as cancer An autoimmune disorder, such as ankylosing spondylitis, rheumatoid arthritis, scleroderma, or sarcoidosis Catamenial, a condition that causes a pneumothorax 1 to 3 days after a woman's monthly period begins What are the signs and symptoms of a spontaneous pneumothorax