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Indeed, young women with depressive or anhedonic vulnerability often report smoking as a form of mood regulation or relief from negative affect 33 , supporting the notion that psychological distress can drive nicotine use in this population

In older adults, loneliness is associated with a 50% increased risk of developing dementia and a 30% increased risk of incident coronary artery disease or stroke

Seemingly an obvious proclamation, or at the least a high ass innuendo

Whether the toxicants attribute to the dysbiosis of intestinal microbiota and whether the toxicants alter intestinal microbiota through sole and/or multiple mechanisms remains to be further determined