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Final Thoughts: From Smoke to Clarity Nicotine may promise calm and clarity to the ADHD brain, but it's a short-term fix with long-term costs

Most people quit and restart several times before they are able to remain smoke-free for the long term

Possible mechanisms can support this claim: nicotine anti-inflammatory effect, a blunted immune response in current smokers and potential high nitric oxide in the upper respiratory airway, which may prevent replication of SARS-CoV-2 and its entry into cells 9

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