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This would also increase the amount of Hes also concerned that reduced nicotine cigarettes may just become another way to entice new users to start smoking

Despite the obvious biologic plausibility, the lack of consistent epidemiological evidence might be due to methodological issues including lack of cohort follow-up time into older adulthood (when lung cancer usually becomes clinically manifest), small sample sizes, selection and recall biases, and lack of adjustment for tobacco use in the statistical modeling

New Engl J Med 329, 15431546 (1993)

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