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Highly dependent subjects who smoked 10 cigarettes per day had higher cotinine levels than low dependent subjects who smoked 20 cigarettes daily (plasma: 326291 vs

Philip Morriss research into EEG, PREP, and CSERP shows that the tobacco company attempted to quantify impact and to monitor the neurological effects of specific additives to maximize cigarette acceptance (which encompasses factors such as cigarette satisfaction and is influenced by a number of elements, including primary reinforcement [e.g., nicotine addiction] and secondary reinforcement115)

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Particularly in view of the higher prices charged for cigarettes nowadays, all these refinements are something of a triumph of merchandising