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The adverse effects of CLO may be dose-dependent and include sedation, drowsiness, dizziness, headache, excessive salivation, postural hypotension, hyperthermia, constipation, myocarditis, weight gain, cardiomyopathy, and seizures (35)

Even though we worked with an expert from each country to ensure the cultural relevance of our predetermined coding categories, it is possible that we underreport the prevalence of feminine packs across countries if specific feminine imagery or terms were not accounted for in our codebook or in the expert review

They wanted to determine how the chemicals providing the main flavor and the nicotine content varied in the versions available in each country

It did come at somewhat of cost, as all but one participant said they felt an unpleasant side effect, including insomnia (75% of participants), weird dreams (72%) or nausea (64%)