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Approaches with real evidence behind them include: Setting a specific quit date and preparing for it in advance Behavioral counseling, whether in person, by phone, or through a text-based program Nicotine replacement options, such as patches, gum, or lozenges, discussed with a physician Prescription medications designed specifically for smoking cessation, when appropriate for the individual Free support through a quitline, such as 1-800-QUIT-NOW Combining more than one of these approaches consistently outperforms trying to quit without any support at all

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This shows that the body is trying to fight off microbes present, much more so than in non-smokers