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Dendritic cells are well-known as the most professional APCs with high expression of major histocompatibility complex (MHC) class II molecules (MHC-II), and they can uptake, process, and present antigens to nave T cells and promote their polarization into different T cell subsets [115]

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Therefore, when creating a two-dimensional Gaussian distribution for the bounding box, the center pixel of the bounding box can be set as the highest weight, which then gradually decreases from the center point to the boundary

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