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To better account for differences in toxicant exposure on health risks, some epidemiologic studies attempted to adjust for the tar and nicotine deliveries of filtered and non-filtered cigarettes by using standardized machine measured tar and nicotine yields reported to the FTC 21

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At the graveyard, before the first briefing takes place, Otacon and Snake discuss Snakes medical test results, which confirm he only has a few months left to live (a year at best)

Smokers sore throat often develops because the throats lining lacks adequate moisture and protection before exposure to heat and smoke