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Tobacco: Nicotine and Dopamine Quitting smoking and vaping is the best thing you can do for your health. It can take multiple attempts to quit, partly due to nicotine. Nicotine is a highly addictive chemical compound Nicotine addiction can become a cycle of dopamine release, withdrawal, and cravings that reinforces continued nicotine use. The tobacco industry profits from keeping this cycle going. What feels like relief is often How does nicotine work

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