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XOR activity was significantly increased in the lung tissues of CS-induced mice, promoted the production of ROS, and involved in CS-induced pulmonary vascular endothelial cells apoptosis through the p53-mediated caspase-dependent apoptosis pathway [122]

This is a major victory for public health officials, but challenges remain

Proponents of a menthol ban decried the practice in a recent letter to the Biden administration, writing: "The predatory marketing of menthol cigarettes and other flavoured tobacco products must be stopped and we should all recognise this as a social justice issue." The letter cites a report that shows about 85% of menthol smokes today are purchased by African Americans, compared to fewer than 10% in the 1950s

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