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Numerous factors have the capacity to provoke oxidative stress, including but not limited to diets rich in fats and sugars, exposure to radiation, thermal stress, specific chemical agents, tobacco use, and excessive intake of alcohol ( Oxidative stress causes lipid peroxidation and ROS-mediated protein modifications, including the formation of cross-links and carbonyl groups or the breaking of polypeptide chains

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His parents separated when he was 3 years old and when his mother was hospitalized with tuberculosis, he was raised by a family friend