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Chronic smoking also leads to the formation of atheromatous plaques due to increased expression of matrix metalloproteinases (MMP), particularly MMP-12 and MMP-9 in macrophages, MMP-8 and MMP-9 in endothelial cells, and MMP-2 and MMP-9 in vascular smooth muscle cells ( 35 , 36 )

Brooks Koepka was seen chewing tobacco while defending his US Open title at Pebble Beach earlier this year, another way of calming your nerves, but due to him being televised so much, cameras couldn't help but pick up Koepka spitting on the course, which a lot of viewers took offence to